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[用于辅助血管显微吻合的腔内可吸收装置。对20只大鼠主动脉的实验研究]

[Intraluminal absorbable device to assist in vascular microanastomosis. Experimental study on 20 rat aortas].

作者信息

Franchi G, Mitrofanoff M, Maladry D, Seknadje P, Mitz V

机构信息

Laboratoire de Microchirurgie, Hôpital Boucicaut, Paris, France.

出版信息

Ann Chir Plast Esthet. 1998 Feb;43(1):7-13.

PMID:9768088
Abstract

The subject of this experimental study is a cylindrical device, with a gauge adjusted to the vessel lumen, which disintegrates in a few minutes. The goal of this device is to increase the reliability of vascular microanastomosis. This study was designed to assess the efficacy and drawbacks of the device. The device is a cylindrical sugar stick, 5 mm long and with a gauge of 1 mm. Ten Wistar rats underwent a standard end-to-end aortic anastomosis with interrupted sutures and ten underwent the same anastomosis with the device placed in the lumen of the proximal and distal vessel. The same surgeon performed all anastomoses. Clamp application time was recorded and anastomotic patency was tested in each case; the vessels were also examined histologically. The clamp application time was significantly lower (p < 0.01), and the patency rate significantly higher (p < 0.01) in the group in which the device was used. There was no histologic sign of intima injury in either group. This very simple device facilitates microanastomosis. It reduces the ischemia time and increases the reliability of the anastomosis, avoiding transfixing sutures. These results suggest that clinical trials are warranted.

摘要

本实验研究的对象是一种圆柱形装置,其规尺可调节至血管腔,该装置在几分钟内会分解。此装置的目的是提高血管显微吻合的可靠性。本研究旨在评估该装置的有效性和缺点。该装置是一根5毫米长、规尺为1毫米的圆柱形糖棒。十只Wistar大鼠接受了标准的端到端主动脉间断缝合吻合术,另外十只在近端和远端血管腔内放置该装置后进行同样的吻合术。所有吻合术均由同一位外科医生进行。记录夹闭时间,并对每种情况测试吻合口通畅情况;还对血管进行了组织学检查。使用该装置的组夹闭时间显著缩短(p < 0.01),通畅率显著提高(p < 0.01)。两组均无内膜损伤的组织学迹象。这种非常简单的装置便于显微吻合。它减少了缺血时间,提高了吻合的可靠性,避免了贯穿缝合。这些结果表明有必要进行临床试验。

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