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[用固相免疫酶法检测犬恶丝虫成虫排泄分泌抗原诊断人体丝虫病]

[Excretion-secretion antigens from adult Dirofilaria immitis in the diagnosis of human filariasis by solid phase immunoenzyme assay].

作者信息

Duménigó Ripoll B, Espíno Hernández A M, Menéndez Valonga M C, Finlay Villalvilla C

机构信息

Instituto de Medicina Tropical Pedro Kouri.

出版信息

Rev Cubana Med Trop. 1991;43(3):162-6.

PMID:9768181
Abstract

The solid phase enzymatic immuno-assay (ELISA) was normalized for detecting antibodies against. Filaria using excretion-secretion antigens (ESA) from Dirofilaria immitis adults in a group of asymptomatic and microfilaraemic patients infected by different species of filariae (loa loa, Wuchereria bancrofti, Onchocerca volvulus, Mansonella ozzardi and Mansonella perstans), and in another group of symptomatic and aminorofilaraemic patients, temporary residents in an area with endemic loiasis. The ESA-ELISA specificity permitted the distinction between filariasic and non-filariasic patients.

摘要

采用固相酶免疫测定法(ELISA),以犬恶丝虫成虫的排泄分泌抗原(ESA)对一组感染不同种类丝虫(罗阿丝虫、班氏吴策线虫、盘尾丝虫、奥氏曼森线虫和常现曼森线虫)的无症状和微丝蚴血症患者以及另一组有症状和轻度微丝蚴血症患者(在罗阿丝虫病流行地区的临时居民)进行抗丝虫抗体检测。ESA-ELISA的特异性有助于区分丝虫病患者和非丝虫病患者。

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