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[用于结核病血清学诊断的酶联免疫吸附测定(ELISA)评估]

[Evaluation of an ELISA for the serologic diagnosis of tuberculosis].

作者信息

Montoro E, Díaz R, Vázquez S, Laferté J, Suárez-Méndez R, Valdivia J A

机构信息

Instituto de Medicina Tropical Pedro Kouri.

出版信息

Rev Cubana Med Trop. 1994;46(2):90-3.

PMID:9768242
Abstract

The use of an ELISA method for the serological diagnosis of tuberculosis was assessed through the study of the presence of circulating IgG antibodies to PPD in 220 serum samples. An 82% sensibility was determined in 50 serum samples from patients with pulmonary tuberculosis, and a specificity of 95.33% in 150 serum samples from apparently healthy subjects. 20 serum samples from patients with disorders other than tuberculosis were included in the study to determine possible cross reactions.

摘要

通过对220份血清样本中循环抗PPD IgG抗体的检测,评估了酶联免疫吸附测定(ELISA)法用于结核病血清学诊断的效果。在50份肺结核患者的血清样本中,该方法的灵敏度为82%;在150份表面健康受试者的血清样本中,特异性为95.33%。研究纳入了20份非结核性疾病患者的血清样本,以确定可能的交叉反应。

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