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[引起皮疹的病毒感染中抗体的异常反应]

[Anomalous response of antibodies in rash-causing viral infections].

作者信息

Resik Aguirre S, Sariol Curbelo C A, Alvarez Vega M, Marrero Suárez M

机构信息

Instituto de Medicina Tropical Pedro Kouri.

出版信息

Rev Cubana Med Trop. 1996;48(1):56-8.

PMID:9768272
Abstract

20 pairs of sera from the National System of Seroepidemiological Surveillance of the triple viral vaccine received in the laboratory with febrile rash diagnosis were studied. By using the hemagglutination inhibition test, it was observed an abnormal answer of antibodies to both rubella and measles through a falling of the antibody titre in one or both diseases, or in one of them with seroconversion to the other one. With the aim of defining the existence of a possible polyclonal activation already described in literature, it was decided to study the antibody response to family Herpesviridae (HSV, EBV, CMV, VZV). 80% of answer to these viruses were found. The results are submitted and discussed.

摘要

对实验室收到的、诊断为发热性皮疹的三联病毒疫苗国家血清流行病学监测系统中的20对血清进行了研究。通过血凝抑制试验,观察到风疹和麻疹抗体出现异常反应,表现为一种或两种疾病的抗体滴度下降,或其中一种疾病抗体滴度下降并伴有血清转化为另一种疾病。为了确定文献中已描述的可能的多克隆激活是否存在,决定研究对疱疹病毒科(单纯疱疹病毒、EB病毒、巨细胞病毒、水痘带状疱疹病毒)的抗体反应。发现对这些病毒有80%的反应。现将结果提交并讨论。

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