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尺寸控制:细胞增殖并不等同于生长。

Size control: cell proliferation does not equal growth.

作者信息

Su T T, O'Farrell P H

机构信息

Department of Biochemistry and Biophysics, University of California San Francisco 94143-0448, USA.

出版信息

Curr Biol. 1998 Sep 24;8(19):R687-9. doi: 10.1016/s0960-9822(98)70436-1.

DOI:10.1016/s0960-9822(98)70436-1
PMID:9768354
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2754256/
Abstract

Division subdivides mass without increasing it. So one should not expect that an increase in cell division would make an organism bigger. Both classic and recent experiments confirm this simple rationale: altering proliferation produces normally sized body structures with either especially small or exceptionally large cells.

摘要

分裂会细分物质但不会增加其总量。因此,人们不应期望细胞分裂的增加会使生物体变大。经典实验和近期实验都证实了这个简单的道理:改变增殖会产生正常大小的身体结构,只是细胞要么特别小,要么异常大。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7075/2754256/ee1053007ed3/nihms142604f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7075/2754256/ee1053007ed3/nihms142604f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7075/2754256/ee1053007ed3/nihms142604f1.jpg

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