Stevens H M, Moffat A C, Drayton J V
Forensic Sci. 1976 Sep-Oct;8(2):131-7. doi: 10.1016/0300-9432(76)90056-x.
A rapid method is described for the extraction and identification of fluoroacetamide and fluoroacetic acid from tissues, by gas chromatography, using a mass spectrometer in the multiple ion monitoring mode as the detector. Recoveries from animal and human tissue macerates, after the addition of each compound, were approximately 30--35% for fluoroacetamide and 50--55% for fluoroacetic acid. Minimum detectable levels in tissues were found to be circa 0.7 mug/g for the amide and 0.1 mug/g for the acid. Visceral tissue levels were found to be approximately 3 mug/g for fluoroacetamide, and 2.5--10 mug/g fluoroacetic acid in guinea pigs and rabbits which had been fatally poisoned with these compounds.
本文描述了一种快速方法，用于从组织中提取和鉴定氟乙酰胺和氟乙酸，采用气相色谱法，使用处于多离子监测模式的质谱仪作为检测器。在向动物和人体组织浸软物中添加每种化合物后，氟乙酰胺的回收率约为30 - 35%，氟乙酸的回收率为50 - 55%。发现组织中的最低检测水平约为酰胺0.7微克/克，酸0.1微克/克。在用这些化合物致死中毒的豚鼠和兔子中，发现内脏组织中氟乙酰胺的含量约为3微克/克，氟乙酸的含量为2.5 - 10微克/克。
