补骨脂素加长波紫外线（PUVA）治疗局限性硬皮病时临床与组织病理学结果在硬度方面的差异。

The discrepancy in hardness between clinical and histopathological findings in localized scleroderma treated with PUVA.

作者信息

Yamaguchi K, Takeuchi I, Yoshii N, Gushi A, Kanekura T, Kanzaki T

机构信息

Department of Dermatology, Kagoshima University, Faculty of Medicine, Japan.

出版信息

J Dermatol. 1998 Aug;25(8):544-6. doi: 10.1111/j.1346-8138.1998.tb02452.x.

DOI:10.1111/j.1346-8138.1998.tb02452.x

PMID:9769602

Abstract

Topical PUVA therapy was applied to a patient with localized scleroderma. Her localized scleroderma responded very well to the topical PUVA therapy, i.e., her sclerotic skin softened to normal skin texture. However, despite this dramatic clinical change the histopathological findings did not change at all and were still "hard".

摘要

对一名局限性硬皮病患者采用了外用补骨脂素加长波紫外线（PUVA）疗法。她的局限性硬皮病对外用PUVA疗法反应非常良好，也就是说，她硬化的皮肤软化至正常的皮肤质地。然而，尽管出现了这种显著的临床变化，组织病理学检查结果却完全没有改变，仍然显示“硬”。