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[强直性脊柱炎的临床特征——流行病学研究]

[Clinical features of ankylosing spondylitis--epidemiologic study].

作者信息

Jajić Z, Grazio S, Nemcić T, Jajić I

机构信息

Klinika za fizikalnu medicinu, rehabilitaciju i reumatologiju, Klinicka bolnica Sestre milosrdnice, Zagreb.

出版信息

Reumatizam. 1997;45(2):13-8.

PMID:9769723
Abstract

The aim of the study was to establish some clinical features of ankylosing spondylitis in an epidemiological study using a mailed questionnaire. The questionnaire was sent to 185 patients with ankylosing spondylitis who were treated at the Department for Physical Medicine, Rehabilitation and Rheumatology. The answers were obtained from 92 patients (49.7%). In the studied cohort there were 60 men and 32 women. The average age of all patients were 51.6 +/- 11.8 yrs. In most of the patients (69 or 75%) the duration of ankylosing spondylitis is more than 15 years. The diagnosis of ankylosing spondylitis was established on average 6.5 years after the beginning of symptoms. Patients suffering from ankylosing spondylitis more than 15 years reported that the worst period of the disease was the starting 10 years. The main symptoms of the disease are stiffness and pain. The aggravation of pain occurs with enhanced physical activity as well as with prolonged rest--Painful swelling of one or more joints of 3 weeks duration had 63.7%, and more than 3 weeks duration 40.7% patients. There was no difference in occurrence of painful swelling extravertebral joints regarding to duration of the disease (P > 0.05). The most often affected joints were hips and shoulders. Eyes inflammation was reported by 63 patients, and unspecified enterocolitis had 16 patients.

摘要

本研究的目的是通过邮寄问卷的方式在一项流行病学研究中确定强直性脊柱炎的一些临床特征。问卷被发送给在物理医学、康复与风湿病科接受治疗的185例强直性脊柱炎患者。从92例患者(49.7%)那里获得了答案。在所研究的队列中,有60名男性和32名女性。所有患者的平均年龄为51.6 +/- 11.8岁。大多数患者(69例或75%)强直性脊柱炎的病程超过15年。强直性脊柱炎的诊断平均在症状出现后6.5年确立。病程超过15年的强直性脊柱炎患者报告称,疾病最严重的时期是开始的10年。该疾病的主要症状是僵硬和疼痛。疼痛加剧发生在体力活动增加以及长时间休息时——持续3周的一个或多个关节疼痛性肿胀的患者有63.7%,持续超过3周的有40.7%。就疾病病程而言,椎体外关节疼痛性肿胀的发生率没有差异(P > 0.05)。最常受累的关节是髋部和肩部。63例患者报告有眼部炎症,16例患者有未明确的小肠结肠炎。

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