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[Synthesis and pharmacologic study of 1,5-benzodiazepine-2,4-diones and their alkyl derivatives].

作者信息

Zellou A, Cherrah Y, Hassar M, Essassi E M

机构信息

Laboratoire de Pharmacologie et de Toxicologie, Faculté de Médecine et de Pharmacie, Rabat Instituts, Maroc.

出版信息

Ann Pharm Fr. 1998;56(4):169-74.

PMID:9770010
Abstract

From the pharmacodynamic studies of 1,5-benzodiazepin-2,4-diones and alkyl derivatives prepared in our laboratories, we can conclude that these products are not toxic at therapeutic dosage. They have sedative, myorelaxant and anxiolytic actions. The two products alkylated by allyl bromide have also hypnotic, sedative and anticonvulsant properties.

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