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[血清胆固醇水平对40-59岁无动脉高血压男性心绞痛远期预后的影响]

[The effect of the blood serum cholesterol level on the late prognosis of stenocardia in men 40-59 years old without arterial hypertension].

作者信息

Prazdnov A S

出版信息

Ter Arkh. 1998;70(8):11-4.

PMID:9770735
Abstract

AIM

To investigate effects of total cholesterol levels in the serum (TC) on angina pectoris (AP) lethality in males.

MATERIALS AND METHODS

The study of 112 males aged 40-59 years with AP without myocardial infarction and blood hypertension lasted for 30-35 years. The examination included determination of lipid-protein blood spectrum, ECG at rest and exercise, other tests. By initial TC levels 98 patients were divided into 2 equal subgroups. Causes of death were ascertained at autopsy (72.0%) or records or regional death and birth registration offices were used. Reliable information was obtained for 98 of 112 patients (87.5%).

RESULTS

At the end of the study 8 of 98 patients were alive (8.2%). In the subgroup with low TC, 2 patients were alive, 47 decreased patients lived, on the average, 69.4 +/- 1.4 years. In the subgroup with high TC, 6 patients were alive, 43 died at the age 71.2 +/- 1.4 years.

CONCLUSION

Individual approach rather than populational is needed for correction of total cholesterol in middle-age and elderly patients with angina pectoris.

摘要

目的

研究男性血清总胆固醇水平(TC)对心绞痛(AP)致死率的影响。

材料与方法

对112名年龄在40 - 59岁、患有心绞痛但无心肌梗死和高血压的男性进行了为期30 - 35年的研究。检查包括脂蛋白血液谱测定、静息和运动心电图以及其他检查。根据初始TC水平,将98名患者分为两个相等的亚组。通过尸检确定死亡原因(72.0%),或使用地区死亡和出生登记办公室的记录。112名患者中有98名(87.5%)获得了可靠信息。

结果

研究结束时,98名患者中有8名存活(8.2%)。在TC水平低的亚组中,2名患者存活,47名病情减轻的患者平均存活69.4±1.4年。在TC水平高的亚组中,6名患者存活,43名患者在71.2±1.4岁时死亡。

结论

对于中年和老年心绞痛患者,总胆固醇的校正需要采用个体化而非群体化方法。

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