Prazdnov A S
Ter Arkh. 1998;70(8):11-4.
To investigate effects of total cholesterol levels in the serum (TC) on angina pectoris (AP) lethality in males.
The study of 112 males aged 40-59 years with AP without myocardial infarction and blood hypertension lasted for 30-35 years. The examination included determination of lipid-protein blood spectrum, ECG at rest and exercise, other tests. By initial TC levels 98 patients were divided into 2 equal subgroups. Causes of death were ascertained at autopsy (72.0%) or records or regional death and birth registration offices were used. Reliable information was obtained for 98 of 112 patients (87.5%).
At the end of the study 8 of 98 patients were alive (8.2%). In the subgroup with low TC, 2 patients were alive, 47 decreased patients lived, on the average, 69.4 +/- 1.4 years. In the subgroup with high TC, 6 patients were alive, 43 died at the age 71.2 +/- 1.4 years.
Individual approach rather than populational is needed for correction of total cholesterol in middle-age and elderly patients with angina pectoris.
研究男性血清总胆固醇水平(TC)对心绞痛(AP)致死率的影响。
对112名年龄在40 - 59岁、患有心绞痛但无心肌梗死和高血压的男性进行了为期30 - 35年的研究。检查包括脂蛋白血液谱测定、静息和运动心电图以及其他检查。根据初始TC水平,将98名患者分为两个相等的亚组。通过尸检确定死亡原因(72.0%),或使用地区死亡和出生登记办公室的记录。112名患者中有98名(87.5%)获得了可靠信息。
研究结束时,98名患者中有8名存活(8.2%)。在TC水平低的亚组中,2名患者存活,47名病情减轻的患者平均存活69.4±1.4年。在TC水平高的亚组中,6名患者存活,43名患者在71.2±1.4岁时死亡。
对于中年和老年心绞痛患者,总胆固醇的校正需要采用个体化而非群体化方法。