Mil'to A S
Ter Arkh. 1998;70(8):54-6.
Study of blood clotting to evaluate hemostatic disorders in infectious endocarditis (IE).
The trial included 124 patients with IE (61 males and 63 females aged 15-70 years). Primary and secondary IE was in 38 and 62% of patients, respectively.
Clinically evident hemostatic disorders were observed in 93(74.2%) cases. They manifested as intravascular platelet activation with development of hypercoagulatory status and chronic DIC-syndrome.
A differentiated approach is advisable to correction of thrombotic disorders in IE basing on the severity of blood coagulation impairment.
研究凝血功能以评估感染性心内膜炎（IE）中的止血障碍。
该试验纳入了124例IE患者（61例男性和63例女性，年龄15 - 70岁）。原发性和继发性IE分别占患者的38%和62%。
93例（74.2%）患者出现了临床明显的止血障碍。表现为血管内血小板激活并伴有高凝状态及慢性弥散性血管内凝血综合征的发展。
基于凝血功能损害的严重程度，对IE中的血栓形成障碍采取差异化的纠正方法是可取的。
