Kursov S V, Khizhniak A A
Anesteziol Reanimatol. 1998 Jul-Aug(4):52-6.
Efficacy of postoperative pancreatitis prevention is assessed in 123 patients with gastric cancer. Pancreatic bloodflow and central hemodynamics were assessed by rheography, activities of serum amylase and free-radical oxidation by biochemiluminescence of blood plasma. After radical surgery on the stomach, disorders of hemocirculation develop in the pancreas, leading to ischemia of the organ and formation of venous congestion; free-radical oxidation is activated and fermenturia increases. Prolonged epidural blocking with lidocaine prevented a decrease of arterial inflow to the pancreas, decreased the intensity of free-radical oxidation, and was more effective than isoptin therapy.
对123例胃癌患者术后胰腺炎预防效果进行评估。通过血流描记法评估胰腺血流和中心血流动力学，通过血浆生物化学发光法评估血清淀粉酶活性和自由基氧化。胃根治性手术后，胰腺血液循环紊乱，导致器官缺血和静脉淤血形成；自由基氧化被激活，尿淀粉酶增加。利多卡因持续硬膜外阻滞可防止胰腺动脉血流减少，降低自由基氧化强度，且比异搏定治疗更有效。
