Meberg R, Kenyon E, Bierman R, Loveland L, Barbosa P
California College of Podiatric Medicine, San Francisco, USA.
J Am Podiatr Med Assoc. 1998 Sep;88(9):442-5. doi: 10.7547/87507315-88-9-442.
Plantar verrucae, caused by human papillomavirus (HPV), are commonly found in patients who have tested positive for the antibodies to human immunodeficiency virus (HIV). A better understanding of the characteristics of plantar verrucae in HIV+ patients in needed. A pilot study was conducted concentrating on three characteristics--the size, the number, and the clinical type--of verrucae present in this population. These parameters were studied in HIV+ and HIV- populations, and they were evaluated in relation to the CD4 levels of HIV+ individuals. The HIV+ individuals presented with plantar verrucae that were larger and more numerous than those found in HIV- individuals. The HIV+ population presented with all three clinical types of plantar verrucae and had significantly more mosaic-type warts than did HIV- individuals. The three characteristics did not correlate with CD4 cell counts, suggesting that the severity and extent of HPV infection do not depend on the level of immunosuppression of the HIV+ patient.
由人乳头瘤病毒（HPV）引起的跖疣，常见于人类免疫缺陷病毒（HIV）抗体检测呈阳性的患者中。有必要更好地了解HIV阳性患者跖疣的特征。开展了一项试点研究，重点关注该人群中疣的三个特征——大小、数量和临床类型。在HIV阳性和HIV阴性人群中研究了这些参数，并根据HIV阳性个体的CD4水平对其进行评估。与HIV阴性个体相比，HIV阳性个体出现的跖疣更大、数量更多。HIV阳性人群出现了所有三种临床类型的跖疣，且镶嵌型疣明显多于HIV阴性个体。这三个特征与CD4细胞计数无关，表明HPV感染的严重程度和范围并不取决于HIV阳性患者的免疫抑制水平。
