Anghileri L J, Heidbreder M
Int J Clin Pharmacol Biopharm. 1976 Jul;14(1):1-5.
Ammonium chloride-induced metabolic acidosis produces an increase of the phosphorus turnover rate in tumor tissue. The lower blood protein-bound 32P seems to indicate that the high phospholipid turnover observed in tumor may be related to an increased molecular degradation. It seems likely that this phenomenon together with the augmented release of phospholipid-bound calcium may induce important changes in the cell membrane behavior.
氯化铵诱导的代谢性酸中毒会使肿瘤组织中的磷周转率增加。血液中与蛋白质结合的32P含量较低，这似乎表明在肿瘤中观察到的高磷脂周转率可能与分子降解增加有关。这种现象连同磷脂结合钙释放的增加似乎可能会引起细胞膜行为的重要变化。
