Bavastrelli M, Midulla M, Rossi D, Salzano M, Calzolari E, Midulla C, Sanguigni S, Torre A, Giardini O
Institute of Pediatrics, "La Sapienza" University of Rome, Rome, Italy, and C.N.R. Institute of Experimental Medicine, Rome, Italy.
J Travel Med. 1998 Jun;5(2):57-60. doi: 10.1111/j.1708-8305.1998.tb00464.x.
The importance of travel as a risk factor for Chlamydia trachomatis infection was evaluated among a series of young people consecutively tested.
We studied 130 sexually active young subjects, aged 14-25 years, all living in the Rome, Italy, urban area. Ninety-eight females and 32 males attended hospital-based clinics or were the partners of an infected female. About half of these subjects had traveled abroad either for pleasure or for work, mostly to Europe, but also to North America or to Asia, where they admitted to having had casual sex. We used two "gold standard" methods to diagnose infection with C. trachomatis: culture on McCoy cells grown in shell vial, and direct immunofluorescence with monoclonal antibodies. Subjects were considered infected when at least one test was positive.
Thirty-nine of 130 (30%) subjects were asymptomatic, and 27/130 (20.8%) subjects were infected with Chlamydia trachomatis, of whom 6/25 (24%) asymptomatic females and 3/14 (21.4%) asymptomatic males were infected. Among teen-aged (ages 14-19) youngsters with more than one sex partner, international travel was an additional significant risk factor for C. trachomatis infection (p<.02; OR 20; 95% CI 1.47-40%). Urethritis/cystitis and vaginal pathology/discharge were the prevalent manifestations of illness among the females, while urethritis was the only clinical condition found in the males.
In a series of young subjects, travel abroad, sex with more than one partner, and teen age, combined together, were significant risk factors for the acquisition of Chlamydia trachomatis genitourinary infection.
在一系列接受连续检测的年轻人中，评估了旅行作为沙眼衣原体感染风险因素的重要性。
我们研究了130名年龄在14至25岁之间、有性活动的年轻受试者，他们均居住在意大利罗马市区。98名女性和32名男性前往医院诊所就诊，或者是受感染女性的伴侣。这些受试者中约有一半曾出国旅游或工作，主要前往欧洲，但也有前往北美或亚洲的，他们承认在国外有过一夜情。我们使用两种“金标准”方法诊断沙眼衣原体感染：在壳瓶中培养的 McCoy 细胞上进行培养，以及用单克隆抗体进行直接免疫荧光检测。当至少一项检测呈阳性时，受试者被视为感染。
130名受试者中有39名（30%）无症状，27/130（20.8%）名受试者感染了沙眼衣原体，其中6/25（24%）无症状女性和3/14（21.4%）无症状男性被感染。在有多个性伴侣的青少年（14至19岁）中，国际旅行是沙眼衣原体感染的另一个重要风险因素（p<0.02；OR 20；95% CI 1.47 - 40%）。尿道炎/膀胱炎和阴道病变/分泌物是女性中常见的疾病表现，而尿道炎是男性中唯一发现的临床病症。
在一系列年轻受试者中，出国旅行、多个性伴侣以及青少年时期这几个因素综合起来，是获得沙眼衣原体泌尿生殖系统感染的重要风险因素。
