Pathological and clinical characteristics of thyroid carcinoma are reported. In 379 routine consecutive autopsies in which carcinoma was not suspected, serial sections of thyroid gland were histologically examined. Latent thyroid carcinoma was detected in 15.7% of the glands. Papillary adenocarcinoma comprised 76.3%, follicular adenocarcinoma 22.0% and trabecular carcinoma 1.7% of the cases. Sclerosing carcinoma was seen in 32 cases. The long diameter of 90% of these tumors was less than 5 mm. Whether or not thyroid carcinoma persists as such a small carcinomatous lesion indefinitely was studied along with its clinical significance. Carcinomatous lesions complicating hyperthyroidism were always less than 1 cm. About 70% were less than 5 mm long. Since proliferation of some thyroid carcinomas was inhibited by TSH suppression therapy, growth and proliferation of carcinoma in the presence of excessive thyroid hormone or hyperthyroidism is probably already inhibited.
报告了甲状腺癌的病理和临床特征。在379例连续进行的常规尸检中，甲状腺未被怀疑患有癌，对甲状腺进行了系列切片的组织学检查。在15.7%的腺体中检测到隐匿性甲状腺癌。乳头状腺癌占病例的76.3%，滤泡状腺癌占22.0%，小梁癌占1.7%。在32例中发现了硬化性癌。这些肿瘤90%的长径小于5毫米。研究了甲状腺癌是否会无限期地以如此小的癌性病变形式存在及其临床意义。并发甲状腺功能亢进的癌性病变总是小于1厘米。约70%的病变长径小于5毫米。由于一些甲状腺癌的增殖受到促甲状腺激素抑制疗法的抑制，在甲状腺激素过多或甲状腺功能亢进的情况下癌的生长和增殖可能已经受到抑制。
