Wang J, Liu G, Wang D, Yuan G, Hou Y, Wang J
Department of Ophthalmology, Affiliated Hospital, Qingdao Medical College, China.
Chin Med J (Engl). 1997 Dec;110(12):946-9.
To investigate the embryonic development of lamina cribrosa of human eyes.
The lamina cribrosa of 291 eyes were studied including 260 eyes taken from embryos and fetus of 7 weeks to full term and 31 eyes from infants under 1 year of age by using light microscopy (LMS), scanning electron microscopy (SEM), and transmission electron microscopy (TEM).
From observations, it was found that the development of the lamina cribrosa was lagged behind the development of the optic nerve.
In eyes taken from embryos or fetus less than 4 months of pregnancy, only ectodermal primordium of the lamina cribrosa could be seen. The initial scleral part of the lamina cribrosa began its formation in the 5th month of fetus. The fibrous tissue originating from the choroid and optic nerve sheath contributed to the formation of the lamina cribrosa in the 8th month fetus. At this time, the morphology of the lamina cribrosa is similar to that of an adult, however the thickness of the structure is still getting increased up to one year after birth.
研究人眼筛板的胚胎发育。
使用光学显微镜（LMS）、扫描电子显微镜（SEM）和透射电子显微镜（TEM），对291只眼睛的筛板进行研究，其中包括260只取自7周龄胚胎及胎儿直至足月的眼睛，以及31只取自1岁以下婴儿的眼睛。
通过观察发现，筛板的发育落后于视神经的发育。
在取自妊娠不足4个月的胚胎或胎儿的眼睛中，仅能看到筛板的外胚层原基。筛板最初的巩膜部分在胎儿第5个月开始形成。源自脉络膜和视神经鞘的纤维组织在胎儿第8个月时有助于筛板的形成。此时，筛板的形态与成人相似，但其结构厚度在出生后1年内仍在增加。
