Ren Z, Li M
Department of Ophthalmology, First School of Clinical Medicine, Beijing Medical University.
Zhonghua Yan Ke Za Zhi. 1995 Mar;31(2):98-101.
Fibrous components and structural morphology of the connective tissue of the lamina cribrosa obtained from 35 normal human autopsy eyes were examined by histochemical staining, transmission electron microscopic and computer-assistant image analytical techniques. Principles of biomechanics were used onto the lamina cribrosa in characterizing its structural and mechanical properties, and in investigating its damage forms, intermediary role between intraocular pressure and optic nerve damage, and intervening factors. We came to the following conclusions: The laminar bundles contain all the three kinds of fibers and behave in such triplex properties as elasticity, plasticity and stiffness. The ellipse shaped transverse section of the lamina cribrosa with the long axis at the vertical meridian, the quadrant variations in the course and density of laminar bundles, and the interindividual variations in the thickness of the lamina cribrosa are responsible for the damage-resistant ability of lamina cribrosa. The intraocular pressure exerts effects upon the lamina cribrosa through two ways, and the damage of the lamina cribrosa is the intermediate link between the insults of the intraocular pressure and the optic nerve damage.
采用组织化学染色、透射电子显微镜及计算机辅助图像分析技术，对35只正常人类尸检眼的筛板结缔组织的纤维成分和结构形态进行了研究。应用生物力学原理来描述筛板的结构和力学特性，研究其损伤形式、眼压与视神经损伤之间的中介作用以及干预因素。我们得出以下结论：板层束包含所有三种纤维，并具有弹性、塑性和刚度等三重特性。筛板呈椭圆形横截面，长轴位于垂直子午线，板层束的走行和密度在象限上存在差异，筛板厚度存在个体间差异，这些因素共同决定了筛板的抗损伤能力。眼压通过两种方式作用于筛板，筛板损伤是眼压损伤与视神经损伤之间的中间环节。
