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[大蒜中的两种新甾体皂苷及其对血液凝固性的抑制作用]

[Two new steroidal saponins from Allium sativum and their inhibitory effects on blood coagulability].

作者信息

Peng J P, Chen H, Qiao Y Q, Ma L R, Narui T, Suzuki H, Okuyama T, Kobayashi H

机构信息

Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing, Japan.

出版信息

Yao Xue Xue Bao. 1996;31(8):607-12.

PMID:9772707
Abstract

Six compunds were isolated from the fresh bulbs of Allium sativum L (garlic). Their structures were elucidated as proto-iso-eruboside-B (I), eruboside-B (II), iso-eruboside-B (III), sativioside C (IV), adenosine (V) and tryptophan (VI). I and III are new steroidal saponins. This paper deals with the structural determination of I and III and their effects on platelet aggregation, blood coagulation and fibrinolysis in vitro.

摘要

从大蒜(葱属植物蒜)的新鲜鳞茎中分离出六种化合物。它们的结构被鉴定为原异红景天苷 - B(I)、红景天苷 - B(II)、异红景天苷 - B(III)、蒜皂苷C(IV)、腺苷(V)和色氨酸(VI)。I和III是新的甾体皂苷。本文论述了I和III的结构测定及其对体外血小板聚集、血液凝固和纤维蛋白溶解的影响。

相似文献

1
[Two new steroidal saponins from Allium sativum and their inhibitory effects on blood coagulability].[大蒜中的两种新甾体皂苷及其对血液凝固性的抑制作用]
Yao Xue Xue Bao. 1996;31(8):607-12.
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Steroidal glycosides from the rhizomes of Anemarrhena asphodeloides and their antiplatelet aggregation activity.萱草根中的甾体糖苷及其抗血小板聚集活性。
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Effects of Chinese drugs "xiebai" and "dasuan" on human platelet aggregation (Allium bakeri, A. sativum).中药“薤白”和“大蒜”(野蒜、大蒜)对人血小板聚集的影响
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