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[支持腰椎穿刺诊断(或灌洗)的理由]

[Reasons in favor of lumbar puncture diagnosis (or lavage)].

作者信息

Schisano G

机构信息

Divisione di Neurochirurgia, Ospedale Nuovo Pellegrini, Napoli.

出版信息

Minerva Anestesiol. 1998 Apr;64(4):135-6.

PMID:9773640
Abstract

In patients with strong suspicion of SAH, CT is the initial diagnostic procedure of choice. A lumbar puncture (LP) should be done if a CT is not available. If the patient has no focal deficit or papilloedema there is a little risk in LP. When a CT is negative there can be indication to do a LP: small leaks can be overlooked by CT, and they are often important premonitory events preceding larger and severe haemorrhages. The accuracy of CT in documenting SAH diminishes after 24 hours: thereafter, diagnosis is often dependent on LP. In some cases LP can be useful because the procedure may alleviate headache and remove some blood. LP can also quantify cerebro-spinal fluid (CSF) pressure, provide a baseline for future CSF determination, and allow the study of some parameters like arachidonate metabolites, lactic acid, fibrinogen degradation products (FDP) and thrombin-antithrombin complex (TAT).

摘要

对于高度怀疑蛛网膜下腔出血(SAH)的患者,CT是首选的初始诊断方法。若无法进行CT检查,则应进行腰椎穿刺(LP)。如果患者没有局灶性神经功能缺损或视乳头水肿,LP的风险较小。当CT检查结果为阴性时,可能需要进行LP:CT可能会漏诊小的出血,而这些小出血往往是更大、更严重出血的重要先兆事件。CT诊断SAH的准确性在24小时后会降低:此后,诊断通常依赖于LP。在某些情况下,LP可能有用,因为该操作可能会缓解头痛并清除一些血液。LP还可以测量脑脊液(CSF)压力,为未来的脑脊液检测提供基线,并有助于研究一些参数,如花生四烯酸代谢产物、乳酸、纤维蛋白原降解产物(FDP)和凝血酶-抗凝血酶复合物(TAT)。

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