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4042对越战时期退伍军人双胞胎中,情感创伤事件和遗传因素对当前身体健康问题报告的影响。

Contribution of emotionally traumatic events and inheritance to the report of current physical health problems in 4042 Vietnam era veteran twin pairs.

作者信息

Eisen S A, Neuman R, Goldberg J, True W R, Rice J, Scherrer J F, Lyons M J

机构信息

VA Medical Center, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri 63106, USA.

出版信息

Psychosom Med. 1998 Sep-Oct;60(5):533-9. doi: 10.1097/00006842-199809000-00001.

Abstract

OBJECTIVE

To determine the contributions of psychological trauma (exposure to combat during the Vietnam War), genetic factors, childhood experiences shared by twin siblings, and unmeasured experiences not shared by twin siblings to the reporting of current physical health problems a mean of 19 years after military service.

METHODS

In 1987, a national sample of 2224 monozygotic and 1818 dizygotic male veteran members of the Vietnam Era Twin Registry participated in a survey of health. Genetic modeling was performed on cross-sectional physical health and combat exposure data derived from Registry twins.

RESULTS

Combat experiences explained a small proportion (0.7-8.4%) of the variance in the report of hypertension, respiratory conditions, persistent skin conditions, gastrointestinal disorders, joint disorders, and hearing problems. Childhood experiences shared by siblings are not clearly related to any health problem studied. By contrast, genetic factors explain 31 to 54% and noncombat experiences not shared by siblings explain 45 to 66% of the variance in current physical health status.

CONCLUSIONS

Greater than 90% of the variance in reported current physical health problems in Vietnam era veterans is attributable to inherited factors and unmeasured environmental experiences not shared by twin siblings. The traumatic experience of combat makes only a small contribution to the report of current physical health problems. These results do not preclude the possibility that combat influenced the prevalence of illness shortly after military service or that combat may influence the development of illness in the future.

摘要

目的

确定心理创伤(越战期间参战经历)、遗传因素、双胞胎兄弟姐妹共有的童年经历,以及双胞胎兄弟姐妹未共有的无法测量的经历,对服役平均19年后报告的当前身体健康问题的影响。

方法

1987年,越南时代双胞胎登记处的2224对同卵双胞胎和1818对异卵双胞胎男性退伍军人全国样本参与了一项健康调查。对登记处双胞胎的横断面身体健康和战斗暴露数据进行了遗传建模。

结果

战斗经历解释了高血压、呼吸系统疾病、持续性皮肤病、胃肠道疾病、关节疾病和听力问题报告中一小部分(0.7 - 8.4%)的差异。兄弟姐妹共有的童年经历与所研究的任何健康问题均无明显关联。相比之下,遗传因素解释了当前身体健康状况差异的31%至54%,兄弟姐妹未共有的非战斗经历解释了45%至66%。

结论

越战时期退伍军人报告的当前身体健康问题差异中,超过90%可归因于遗传因素和双胞胎兄弟姐妹未共有的无法测量的环境经历。战斗的创伤经历对当前身体健康问题报告的影响很小。这些结果并不排除战斗在服役后不久影响疾病患病率,或战斗可能在未来影响疾病发展的可能性。

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