Gambaro G, Patrassi G, Pittarello F, Nardellotto A, Checchetto S, D'Angelo A
Institute of Internal Medicine, Division of Nephrology, University of Padua, Italy.
Am J Kidney Dis. 1998 Oct;32(4):657-60. doi: 10.1016/s0272-6386(98)70032-0.
It has long been known that patients with nephrotic syndrome have a hypercoagulable state, which explains the association between nephrotic syndrome, renal vein thrombosis, and thromboembolism. However, the Budd-Chiari syndrome has never been reported in nephrotic patients. This is the first report of such an association that, most likely, depended on a primary resistance to activated protein C.
长期以来,人们都知道肾病综合征患者处于高凝状态,这解释了肾病综合征、肾静脉血栓形成和血栓栓塞之间的关联。然而,布加综合征从未在肾病患者中被报道过。这是关于这种关联的首次报告,很可能是由于对活化蛋白C的原发性抵抗所致。