Burmaster D E, Murray D M
Alceon Corporation, Cambridge, Massachusetts 02238-2669, USA.
Risk Anal. 1998 Aug;18(4):385-9. doi: 10.1111/j.1539-6924.1998.tb00352.x.
Using exploratory data analysis, probability plots, scatterplots, and computer animations to rotate and visualize the data, we fit a trivariate Normal distribution to data for the height, the natural logarithm of body weight, and the body fat for 646 men between the ages of 50 and 80 years as reported by the medical staff of the U.S. Veterans Administration's "Normative Aging Study" in Boston, MA. Although these data do not include any children, women, or young men, the measurements represent the best data that we could find through a 4-year search. We believe that these data are well measured and reliable for men in the specified age range and that these data reveal an interesting statistical pattern for use in probabilistic PBPK models.
通过探索性数据分析、概率图、散点图以及使用计算机动画来旋转和可视化数据，我们对马萨诸塞州波士顿市美国退伍军人管理局“规范老化研究”的医务人员报告的646名年龄在50至80岁之间男性的身高、体重自然对数和体脂数据拟合了一个三元正态分布。尽管这些数据不包括任何儿童、女性或年轻男性，但这些测量值是我们经过4年搜索所能找到的最佳数据。我们相信，这些数据对于指定年龄范围内的男性来说测量良好且可靠，并且这些数据揭示了一种有趣的统计模式，可用于概率性生理药代动力学（PBPK）模型。
