Thomas W B
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville 37901-1071, USA.
Clin Tech Small Anim Pract. 1998 Aug;13(3):167-78. doi: 10.1016/S1096-2867(98)80038-8.
Inflammatory diseases of the central nervous system (CNS) are important causes of seizures in dogs. Specific diseases include canine distemper, rabies, cryptococcosis, coccidioidomycosis, toxoplasmosis, neosporosis, Rocky Mountain spotted fever, ehrlichiosis, granulomatous meningoencephalomyelitis, and pug dog encephalitis. Inflammatory disorders should be considered when a dog with seizures has persistent neurological deficits, suffers an onset of seizures at less than 1 or greater than 5 years of age, or exhibits signs of systemic illness. A thorough history, examination, and analysis of cerebrospinal fluid are important in the diagnosis of inflammatory diseases. However, even with extensive diagnostic testing, a specific etiology is identified in less than two thirds of dogs with inflammatory diseases of the CNS.
中枢神经系统（CNS）炎症性疾病是犬类癫痫发作的重要原因。具体疾病包括犬瘟热、狂犬病、隐球菌病、球孢子菌病、弓形虫病、新孢子虫病、落基山斑疹热、埃立克体病、肉芽肿性脑膜脑脊髓炎和哈巴狗脑炎。当患有癫痫的犬出现持续性神经功能缺损、在1岁以下或5岁以上首次发作癫痫或表现出全身疾病迹象时，应考虑炎症性疾病。详尽的病史、检查和脑脊液分析对炎症性疾病的诊断很重要。然而，即便进行了广泛的诊断测试，在不到三分之二的患有中枢神经系统炎症性疾病的犬中能确定具体病因。
