Pruett J H, Temeyer K B, Fisher W F, Beetham P K, Kunz S E
Knipling-Bushland U.S. Livestock Insects Research Laboratory, USDA-ARS, Kerrville, TX 78028-9184, USA.
J Med Entomol. 1998 Sep;35(5):861-71. doi: 10.1093/jmedent/35.5.861.
In this study potential vaccine candidate immunogens were identified and evaluated in a vaccine challenge trial. Calves vaccinated with a partially purified fraction of Psoroptes ovis-soluble proteins had 8 of 14 calves free of palpable lesions 8 wk after a challenge infestation. A self-grooming behavioral response elicited by a pruritic immediate-type allergic reaction was believed to be an effector in protecting the vaccinated calves from a clinical P. ovis infestation.
在本研究中，在疫苗攻毒试验中鉴定并评估了潜在的疫苗候选免疫原。用部分纯化的绵羊痒螨可溶性蛋白组分接种的犊牛，在攻毒感染8周后，14头中有8头没有明显病变。由瘙痒速发型过敏反应引发的自我梳理行为反应被认为是保护接种犊牛免受临床绵羊痒螨感染的一种效应机制。
