Ferguson C A, Whyman R A
Dental Department, Wellington Hospital.
N Z Dent J. 1998 Sep;94(417):125-30.
Chronic renal failure is the result of progressive loss of functioning nephrons leading to loss of renal function and accumulation of excretory products. Loss of the regulatory and excretory functions of the kidneys causes oral manifestations and multiple complications which have implications for dental care. Dental management of patients with renal failure and renal transplants involves consideration of specific haematological and cardiovascular effects, and implications for the prescribing and use of pharmaceuticals. It also requires the dentist to appreciate the potential for involvement of multiple organ systems in the disease process and the implications this has for dental care. The orofacial manifestations of chronic renal failure are secondary to systemic manifestations and are not specific to the diagnosis of end-stage renal disease.
慢性肾衰竭是功能性肾单位逐渐丧失的结果，导致肾功能丧失和排泄产物蓄积。肾脏调节和排泄功能的丧失会引起口腔表现和多种并发症，这些对牙科护理有影响。肾衰竭和肾移植患者的牙科管理涉及对特定血液学和心血管影响的考虑，以及对药物处方和使用的影响。这也要求牙医认识到疾病过程中多器官系统受累的可能性及其对牙科护理的影响。慢性肾衰竭的口面部表现是全身表现的继发表现，并非终末期肾病诊断所特有的。
