一名烧伤患者的抗精神病药物恶性综合征

Neuroleptic malignant syndrome in a burn patient.

作者信息

Still J, Friedman B, Law E, Deppe S, Epperly N, Orlet H

机构信息

Columbia-Augusta Medical Center, Augusta, GA 30914-3726, USA.

出版信息

Burns. 1998 Sep;24(6):573-5. doi: 10.1016/s0305-4179(98)00056-4.

DOI:10.1016/s0305-4179(98)00056-4

PMID:9776099

Abstract

A 39 year old white male with a 55% total body surface burn who developed neuroleptic malignant syndrome (NMS) during his acute course is reported. The patient had several acute sinusitis and septic episodes during his acute course. On postburn day 31, he developed a temperature of 108.4 degrees F (42.4 degrees C). This responded promptly to Dantrolene and Bromocriptene. His recovery was uneventful. NMS is a drug-related response to various medications, such as Haloperidol, which the patient was receiving. NMS must be considered as part of the differential diagnosis of fever in burn patients receiving medication known to cause the syndrome.

摘要

报告了一名39岁的白人男性，其全身55%体表烧伤，在急性期发生了抗精神病药恶性综合征（NMS）。该患者在急性期有几次急性鼻窦炎和脓毒症发作。烧伤后第31天，他体温升至108.4华氏度（42.4摄氏度）。这对丹曲林和溴隐亭反应迅速。他康复过程顺利。NMS是对多种药物（如患者正在使用的氟哌啶醇）的药物相关反应。在接受已知可导致该综合征的药物治疗的烧伤患者中，必须将NMS视为发热鉴别诊断的一部分。