猿猴病毒40介绍：在宿主细胞的鼎力相助下生存繁衍

Introduction to simian virus 40: getting by with more than a little help from its host cell.

作者信息

Fanning E

机构信息

Department of Molecular Biology, Vanderbilt University, Nashville, TN 37235, USA.

出版信息

Dev Biol Stand. 1998;94:3-8.

PMID:9776219

Abstract

More than three decades of research on simian vacuolating virus 40 (SV40) have generated a richly detailed picture of the viral genome, the events in infection, and the functions of the viral proteins in the host cell. This contribution briefly reviews our current understanding of SV40 biology as an introduction to this symposium volume on its role as a possible human polyoma-virus.

摘要

三十多年来对猴空泡病毒40（SV40）的研究，已经勾勒出一幅关于病毒基因组、感染过程以及病毒蛋白在宿主细胞中功能的详尽图景。本论文简要回顾了我们目前对SV40生物学的理解，以此作为本次关于其作为一种可能的人类多瘤病毒作用的研讨会文集的引言。