Blaas H G, Eik-Nes S H, Berg S, Torp H
National Center for Fetal Medicine, Department of Obstetrics and Gynaecology, Trondheim University Hospital, Norway.
Lancet. 1998 Oct 10;352(9135):1182-6. doi: 10.1016/S0140-6736(98)03227-9.
Three-dimensional (3D) imaging of the living human embryo has become possible in the monitoring of embryological development, as described by classic human embryology. We aimed to create 3D images of organs in embryos on early pregnancy.
We used a specially developed 7.5 MHz annular array 3D transvaginal probe to examine embryos. We included 34 women at 7-10 weeks' gestation. We measured the crown-rump length (CRL) of the embryos and fetuses and transferred the 3D ultrasound data to an external computer for further processing to calculate volume.
The CRLs ranged from 9.3 mm to 39.0 mm. The quality of the images of the embryos and fetuses made it possible to outline in detail the outer contours and the contours of the brain cavities, and the calculated volumes corresponded well to the descriptions from classic human embryology.
Our 3D imaging system allowed visualisation of structures of less than 10 mm. Therefore, development and abnormal development of fetuses can be monitored.
如经典人体胚胎学所述，对活体人类胚胎进行三维（3D）成像已成为监测胚胎发育的可能。我们旨在创建妊娠早期胚胎器官的3D图像。
我们使用专门开发的7.5兆赫环形阵列3D经阴道探头检查胚胎。我们纳入了34名妊娠7至10周的女性。我们测量了胚胎和胎儿的头臀长度（CRL），并将3D超声数据传输到外部计算机进行进一步处理以计算体积。
CRL范围为9.3毫米至39.0毫米。胚胎和胎儿图像的质量使得能够详细勾勒出外部轮廓和脑腔轮廓，并且计算出的体积与经典人体胚胎学的描述非常吻合。
我们的3D成像系统能够可视化小于10毫米的结构。因此，可以监测胎儿的发育和异常发育情况。
