Krieger R I, South P, Mendez Trigo A, Flores I
Department of Entomology, University of California, Riverside 92521, USA.
Vet Hum Toxicol. 1998 Oct;40(5):267-9.
Methomyl (S-methyl-N-((methylcarbamoyl)oxy) thioacetimidate) toxicity was studied in horses using i.v. dosages from 0.01 to 3.0 mg/kg. Doses of 1-3 mg methomyl/kg produced increased GI motility and respirations, facial fasiculations, salivation, lacrimation and convulsions. The only effect at 0.5 mg/kg was increased GI sounds in 1/4 horses. This extensively used crop insecticide had been associated with episodes of morbidity and mortality and led to speculation that it was extremely potent to the horse. This was not supported by these clinical studies.
使用静脉注射剂量为0.01至3.0毫克/千克的灭多威（S-甲基-N-（（甲基氨基甲酰基）氧基）硫代乙脒）对马进行毒性研究。灭多威剂量为1-3毫克/千克时，可导致胃肠蠕动增加、呼吸加快、面部抽搐、流涎、流泪和惊厥。0.5毫克/千克剂量时，仅1/4的马出现胃肠声音增强。这种广泛使用的农作物杀虫剂曾与发病和死亡事件有关，有人据此推测它对马具有极强的毒性。但这些临床研究并不支持这一观点。
