Willemse R B, Egeler-Peerdeman S M
Department of Neurosurgery, University Hospital Vrije Universiteit, Amsterdam, The Netherlands.
Acta Neurochir Suppl. 1998;71:37-9. doi: 10.1007/978-3-7091-6475-4_11.
The retrospective results of external lumbar drainage in 7 adult patients with severe closed head injury and intracranial pressure (ICP) refractory to aggressive management strategies are presented. All patients had Glasgow Coma Scale (GCS) scores of 8 or less within 24 hours after admission and were treated by a staircase protocol including sedation, ventricular drainage, hyperventilation and mannitol. In three cases barbiturate drugs and an artificially induced hypothermia were used. Four patients required surgical evacuation of mass lesions. Three patients made a good functional recovery, 2 were severely disabled and 2 patients died. In none of the patients clinical signs of cerebral herniation occurred. We recommend additional external lumbar drainage in adults with severe head injury unresponsive to aggressive ICP control with open basilar cisterns and absent focal mass lesions on computerized-tomography scan before drainage.
本文介绍了7例成年重度闭合性颅脑损伤患者采用腰大池外引流术的回顾性研究结果,这些患者的颅内压(ICP)对积极的治疗策略无效。所有患者入院后24小时内格拉斯哥昏迷量表(GCS)评分均为8分或更低,并接受了包括镇静、脑室引流、过度通气和甘露醇治疗的阶梯式方案。3例患者使用了巴比妥类药物和人工诱导低温治疗。4例患者需要手术清除占位性病变。3例患者功能恢复良好,2例严重残疾,2例死亡。所有患者均未出现脑疝的临床体征。我们建议,对于成年重度颅脑损伤患者,若在引流前计算机断层扫描显示基底池开放且无局灶性占位性病变,而积极控制ICP无效时,可加用腰大池外引流术。