关节炎的古老性：在北美古新世发现的脊柱关节病。关闭。 （注：原文“off.”不太明确其准确含义，这里暂且直译）
Antiquity of arthritis: spondyloarthropathy identified in the Paleocene of North America. off.
作者信息
Rothschild B M, Sebes J I, Rothschild C
机构信息
Arthritis Center of Northeast Ohio, Youngstown 44512, USA.
出版信息
Clin Exp Rheumatol. 1998 Sep-Oct;16(5):573-5.
OBJECTIVE
Determination of the antiquity of spondyloarthropathy by examining the fossil record.
METHODS
Fossil collections from the Paleocene and Eocene of North America were systematically examined to determine the occurrence and population frequency of spondyloarthropathy.
RESULTS
Spondyloarthropathy was present in three mammalian orders dated at 30 to 50 million years. The frequency was 13% to 50% in the affected genera.
CONCLUSIONS
Erosive arthritis of the spondyloarthropathy variety is now documented to have originated at least 40 million years ago in the Paleocene.
目的
通过检查化石记录来确定脊柱关节病的古老程度。
方法
系统检查了来自北美洲古新世和始新世的化石标本，以确定脊柱关节病的出现情况和种群频率。
结果
脊柱关节病存在于三个哺乳动物目中，年代可追溯到3000万至5000万年前。在受影响的属中，频率为13%至50%。
结论
现已证明，脊柱关节病类型的侵蚀性关节炎至少在4000万年前的古新世就已出现。
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