Yakabi K, Nakamura T
3rd Department of Internal Medicine, Teikyo University School of Medicine, Ichihara Hospital.
Nihon Rinsho. 1998 Sep;56(9):2336-42.
AGML (acute gastric mucosal lesion) is now recognized as one of the important causal disease for gastrointestinal bleeding. If patients have sudden onsets of epigastralgia, epigastric discomfort, vomiting, hematemesis and melena following probable causes, it seems quite reasonable to make diagnosis of AGML by endoscopy with findings of gastric erosion, hemorrhagic gastritis and gastric ulcer. There are a variety of causes for AGML such as psychological and physical stress, drugs (NSAIDs, antibiotics, adrenal corticoid steroid, anti cancer drug), alcohol, serious organ failure of liver, kidney, heart, anisakiasis and etc. There are aslso a variety of endoscopic findings of AGML such as redness, edema, erosion, ulcer, bleeding which vary quickly in a short time. In this article we describe the definition, the cause, the clinical course, the location, the diagnosis, the endoscopic findings, our cases, the treatment of AGML.
急性胃黏膜病变(AGML)现被认为是胃肠道出血的重要病因之一。如果患者在可能的病因之后突然出现上腹部疼痛、上腹部不适、呕吐、呕血和黑便,通过内镜检查发现胃黏膜糜烂、出血性胃炎和胃溃疡来诊断AGML似乎是相当合理的。AGML有多种病因,如心理和身体应激、药物(非甾体抗炎药、抗生素、肾上腺皮质类固醇、抗癌药)、酒精、严重的肝、肾、心器官功能衰竭、异尖线虫病等。AGML的内镜检查结果也多种多样,如发红、水肿、糜烂、溃疡、出血,且在短时间内变化很快。在本文中,我们描述了AGML的定义、病因、临床病程、部位、诊断、内镜检查结果、我们的病例以及治疗方法。