Kaffe I, Ardekian L, Peled M, Machtey E, Laufer D
Department of Oral Pathology and Oral Medicine, Maurice and Gabriela Goldschleger School of Dental Medicine, Tel Aviv University, Israel.
Dentomaxillofac Radiol. 1998 Jul;27(4):209-14. doi: 10.1038/sj/dmfr/4600351.
To analyse the clinical and radiological features of primary intra-osseous carcinoma of the jaws (PIOC).
Twenty-four cases (23 from the literature and one new case) of PIOC were reviewed.
Patient's age at time of diagnosis ranged from 4-76 years, (mean 50 years). Male to female ratio was 1.7:1. Most lesions (79%) were in the mandible and of these, 95% were in the posterior area, approximately 70% of the maxillary lesions were in the anterior region and crossed the midline. In 87% of the cases PIOC was radiolucent; the remainder were mixed radiolucent-radiopaque lesions. The radiological borders were defined but none corticated in 57% of the cases and diffuse in 43%. The lesion was unilocular in 61% and not loculated in 35%.
The variable radiological features of PIOC and its deceptive resemblance to odontogenic cysts and other tumours of the jaws suggests that despite its rarity, PIOC should be considered in the differential diagnosis of radiolucent lesions in the jaws.
分析颌骨原发性骨内癌(PIOC)的临床和影像学特征。
回顾了24例PIOC病例(23例来自文献,1例为新病例)。
诊断时患者年龄范围为4至76岁(平均50岁)。男女比例为1.7:1。大多数病变(79%)位于下颌骨,其中95%位于后部区域,约70%的上颌病变位于前部区域并跨越中线。87%的病例中PIOC呈透射性;其余为透射性与阻射性混合病变。57%的病例影像学边界清晰但无皮质骨,43%呈弥漫性。61%的病变为单房性,35%无分隔。
PIOC多样的影像学特征及其与牙源性囊肿和颌骨其他肿瘤的相似性提示,尽管PIOC罕见,但在颌骨透射性病变的鉴别诊断中应考虑到它。