Hatron P Y
Service de médecine interne A, Hôpital Claude-Huriez, Lille.
Rev Prat. 1998 Mar 15;48(6):620-5.
During the past few years, changes in the spectrum of serious forms of systemic lupus erythematosus have been observed, and generally, the prognosis has improved. This results from a better understanding of the mechanisms of some visceral involvements (especially cerebral and cardiovascular), from the characterization of the antiphospholipid antibodies syndrome, and from a better management. As a result, kidney and central nervous system involvements are not the main causes of mortality any more. However, increasing survival leads to a higher frequency of some late complications, especially related to atherosclerosis.
在过去几年中，已观察到系统性红斑狼疮严重形式的谱有所变化，总体而言，预后有所改善。这得益于对一些内脏受累（尤其是脑和心血管）机制的更好理解、抗磷脂抗体综合征的特征描述以及更好的管理。因此，肾脏和中枢神经系统受累不再是主要的死亡原因。然而，生存率的提高导致一些晚期并发症的发生率增加，尤其是与动脉粥样硬化相关的并发症。
