Miller B L, Cummings J, Mishkin F, Boone K, Prince F, Ponton M, Cotman C
Department of Neurology, University of California Los Angeles School of Medicine, USA.
Neurology. 1998 Oct;51(4):978-82. doi: 10.1212/wnl.51.4.978.
To describe the clinical, neuropsychological, and imaging features of five patients with frontotemporal dementia (FTD) who acquired new artistic skills in the setting of dementia.
Creativity in the setting of dementia has recently been reported. We describe five patients who became visual artists in the setting of FTD.
Sixty-nine FTD patients were interviewed regarding visual abilities. Five became artists in the early stages of FTD. Their history, artistic process, neuropsychology, and anatomy are described.
On SPECT or pathology, four of the five patients had the temporal variant of FTD in which anterior temporal lobes are involved but the dorsolateral frontal cortex is spared. Visual skills were spared but language and social skills were devastated.
Loss of function in the anterior temporal lobes may lead to the "facilitation" of artistic skills. Patients with the temporal lobe variant of FTD offer a window into creativity.
描述五例额颞叶痴呆（FTD）患者在痴呆背景下获得新艺术技能的临床、神经心理学和影像学特征。
近期有关于痴呆背景下创造力的报道。我们描述了五例在FTD背景下成为视觉艺术家的患者。
对69例FTD患者进行了视觉能力方面的访谈。其中五例在FTD早期成为艺术家。描述了他们的病史、艺术创作过程、神经心理学和解剖学情况。
在单光子发射计算机断层扫描（SPECT）或病理学检查中，五例患者中有四例患有FTD的颞叶变异型，即前颞叶受累但背外侧额叶皮质未受影响。视觉技能得以保留，但语言和社交技能严重受损。
前颞叶功能丧失可能导致艺术技能的“激发”。FTD颞叶变异型患者为研究创造力提供了一个窗口。
