慢性恰加斯病的尸检诊断：心包液三种血清学检测的比较评估

Post-mortem diagnosis of chronic Chagas's disease comparative evaluation of three serological tests on pericardial fluid.

作者信息

Lopes E R, Chapadeiro E, Batista S M, Cunha J G, Rocha A, Miziara L, Ribeiro J U, Patto R J

出版信息

Trans R Soc Trop Med Hyg. 1978;72(3):244-6. doi: 10.1016/0035-9203(78)90202-x.

Abstract

In an attempt to improve the post-mortem diagnosis of Chagas's disease the authors performed haemagglutination tests (HAT), fluorescent Trypanosoma cruzi antibody tests (FAT), and complement fixation tests (CFT) on the pericardial fluid obtained at autopsy of 50 individuals with Chagas's heart disease, and 93 patients in whom this disease was not thought to be present. The results demonstrate that all three tests are efficient for the post-mortem diagnosis of Chagas's disease but suggest that their combined use would detect more cases than would one isolated reaction only.

摘要

为了改进恰加斯病的尸检诊断，作者对50例恰加斯心脏病患者尸检时获取的心包液，以及93例被认为不存在该病的患者的心包液进行了血凝试验（HAT）、荧光克氏锥虫抗体试验（FAT）和补体结合试验（CFT）。结果表明，这三种试验对恰加斯病的尸检诊断均有效，但提示联合使用比仅采用一种单独反应能检测出更多病例。