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窦腔穿刺在重症监护病房鼻窦炎治疗中的作用。

Role of antral puncture in the treatment of sinusitis in the intensive care unit.

作者信息

Ramadan H H, Owens R M, Tiu C, Wax M K

机构信息

Department of Otolaryngology-Head and Neck Surgery, West Virginia University, Morgantown 26506-9200, USA.

出版信息

Otolaryngol Head Neck Surg. 1998 Oct;119(4):381-4. doi: 10.1016/S0194-5998(98)70083-X.

Abstract

OBJECTIVE

The objective of this study was to determine whether maxillary sinus puncture caused an alteration in antibiotic treatment and thus affected the outcome of sinusitis in the intensive care unit.

STUDY DESIGN

A retrospective review was done of cases of maxillary sinus puncture between 1991 and 1994.

RESULTS

Forty-two patients were identified. All patients had findings suggestive of sinusitis on plain sinus films or CT scans of the sinuses. Twenty-five punctures (60%) recovered pus, of which 80% grew organisms. Fourteen patients (33%) had a negative lavage, and 12% of these samples grew organisms (p = 0.001). Sixty-eight percent of the cultures identified a single organism compared with 32% with multiple organisms. Gram-negative organisms were found most commonly, followed by anaerobes. In 57% of the cases antibiotic therapy was changed. In 77% of the cases the change was directed by the culture result and in 35% the therapy was changed despite a negative culture result (p = 0.002). Resolution of symptoms occurred in 83% of patients who had antibiotics changed whereas with no change in antibiotics only 42% had resolution (p = 0.001).

CONCLUSION

A sinus puncture seems to be helpful in patients with fever and positive findings on sinus films. If pus is obtained by maxillary puncture, a positive culture may be found in 80% of the cases. Changes in antibiotic regimen on the basis of culture findings seem to give a better outcome.

摘要

目的

本研究的目的是确定上颌窦穿刺是否会导致抗生素治疗的改变,从而影响重症监护病房中鼻窦炎的治疗结果。

研究设计

对1991年至1994年间上颌窦穿刺病例进行回顾性研究。

结果

共确定42例患者。所有患者在鼻窦平片或鼻窦CT扫描上均有提示鼻窦炎的表现。25次穿刺(60%)抽出脓液,其中80%培养出微生物。14例患者(33%)灌洗结果为阴性,这些样本中有12%培养出微生物(p = 0.001)。68%的培养物鉴定出单一微生物,32%为多种微生物。最常发现革兰氏阴性菌,其次是厌氧菌。57%的病例抗生素治疗发生了改变。77%的病例改变是根据培养结果进行的,35%的病例尽管培养结果为阴性仍改变了治疗方案(p = 0.002)。抗生素治疗改变的患者中83%症状得到缓解,而未改变抗生素治疗的患者中只有42%症状得到缓解(p = 0.0)。

结论

鼻窦穿刺似乎对发热且鼻窦片有阳性表现的患者有帮助。如果通过上颌窦穿刺获得脓液,80%的病例可能培养出阳性结果。根据培养结果改变抗生素治疗方案似乎能取得更好的治疗效果。

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