Steinbok P, Schrag C
Division of Neurosurgery, Department of Surgery, University of British Columbia, and Division of Neurosurgery, Section of Surgery, British Columbia's Children's Hospital, Vancouver, Canada.
Pediatr Neurosurg. 1998 Jun;28(6):300-13. doi: 10.1159/000028668.
Selective dorsal rhizotomy (SDR) has been shown to be an effective treatment for the spasticity of cerebral palsy, but few studies have addressed specifically the side effects of the procedure. A retrospective study was performed to determine the frequency and nature of complications in 158 children who had undergone SDR at British Columbia's Children's Hospital from 1987 to 1996. Intraoperative, preoperative (immediate postoperative until discharge at approximately 7 days) and postdischarge complications occurred in 3.8, 43.6 and 30% of patients, respectively. The most common intraoperative complication was aspiration pneumonia, which was experienced by 2 patients (1.3%). Perioperatively, sensory changes were found in 8.9% of the children, and transient urinary retention in 4.4%. Complications after discharge included back pain starting more than 6 months after surgery in 10.8%, sensory changes in 13.9%, and neurogenic bladder or bowel problems in 12.7%. Persistent sensory changes occurred in 3.8%, were not important functionally, and tended to occur in patients with the largest amount of dorsal root tissue cut. In 8 patients (5.1%), bladder and/or bowel dysfunction attributed to the SDR was present at the latest follow-up, although in only 2 patients (1.3%) this dysfunction was a definite complication of the rhizotomy. The use of pudendal monitoring and/or cutting less than 50% of the S2 roots may have been associated with a lower incidence of long-term sphincter dysfunction. Data about the nature and frequency of complications may result in further modifications to the SDR procedure, and is critical for counseling about SDR and alternative options available for treatment of the child with spastic cerebral palsy.
选择性背根切断术(SDR)已被证明是治疗脑瘫痉挛的有效方法,但很少有研究专门探讨该手术的副作用。进行了一项回顾性研究,以确定1987年至1996年在不列颠哥伦比亚省儿童医院接受SDR手术的158名儿童并发症的发生频率和性质。术中、术前(术后即刻至约7天出院)和出院后并发症的发生率分别为3.8%、43.6%和30%。最常见的术中并发症是吸入性肺炎,有2名患者(1.3%)出现该并发症。围手术期,8.9%的儿童出现感觉变化,4.4%出现短暂性尿潴留。出院后的并发症包括术后6个月以上出现的背痛(10.8%)、感觉变化(13.9%)以及神经源性膀胱或肠道问题(12.7%)。持续的感觉变化发生率为3.8%,功能上并不重要,且往往发生在背根组织切除量最大的患者中。在最近一次随访时,8名患者(5.1%)存在归因于SDR的膀胱和/或肠道功能障碍,不过只有2名患者(1.3%)的这种功能障碍是明确的背根切断术并发症。使用阴部监测和/或切除少于50%的S2神经根可能与较低的长期括约肌功能障碍发生率有关。关于并发症的性质和频率的数据可能会导致对SDR手术的进一步改进,对于为患有痉挛性脑瘫的儿童提供SDR咨询以及其他可用治疗选择至关重要。