Ghazi A, Berrier C, Ajouz B, Besnard M
Laboratoire des Biomembranes, ERS 571 CNRS, Université Paris-Sud, Orsay, France.
Biochimie. 1998 May-Jun;80(5-6):357-62. doi: 10.1016/s0300-9084(00)80003-6.
Mechanosensitive channels are ion channels whose activity is dependent on a mechanical stress on the membrane. They are believed to play a central role in mechanotransduction, the process by which mechanical energy is converted into electrical or chemical signals in biological cells. Recent progress, which has been made at the molecular level, is presented, and the two current models of activation of these channels are discussed.
机械敏感通道是一类离子通道，其活性依赖于细胞膜上的机械应力。它们被认为在机械转导过程中起着核心作用，机械转导是指机械能在生物细胞中转化为电信号或化学信号的过程。本文介绍了在分子水平上取得的最新进展，并讨论了这些通道激活的两种当前模型。
