神经元烟碱型乙酰胆碱受体的变构调节
Allosteric modulation of neuronal nicotinic acetylcholine receptors.
作者信息
Buisson B, Bertrand D
机构信息
Department of Physiology, Medical Faculty, Geneva, Switzerland.
出版信息
J Physiol Paris. 1998 Apr;92(2):89-100. doi: 10.1016/S0928-4257(98)80144-7.
PMID:9782450
Abstract
The structure-function relationship of the neuronal nicotinic acetylcholine receptor is examined in the light of the allosteric concepts. Effects of site-directed mutagenesis as well as those caused by allosteric effector of the physiological and pharmacological receptor properties are discussed.
摘要
根据变构概念研究神经元烟碱型乙酰胆碱受体的结构-功能关系。讨论了定点诱变的作用以及由变构效应剂引起的生理和药理受体特性的作用。
Zotero 插件