David W S, Roehr C L, Leatherman J W
Department of Neurology, Hennepin County Medical Center, Minneapolis, Minnesota, USA.
Electromyogr Clin Neurophysiol. 1998 Sep;38(6):371-6.
We have reviewed the clinical and electrophysiologic features of eleven mechanically ventilated patients with asthma who developed persistent weakness following treatment with neuromuscular blocking agents and corticosteroids. All patients had electrophysiologic findings consistent with a myopathic process and no evidence of a neuromuscular transmission disorder or generalized neuropathy. Electrophysiologic improvement paralleled clinical improvement. The severity of the initial electrophysiologic findings did not predict the subsequent rate of recovery. All patients showed substantial recovery (to functional independence) over the first month.
我们回顾了11例机械通气的哮喘患者的临床和电生理特征，这些患者在接受神经肌肉阻滞剂和皮质类固醇治疗后出现了持续性肌无力。所有患者的电生理检查结果均符合肌病过程，且无神经肌肉传递障碍或全身性神经病变的证据。电生理改善与临床改善平行。最初电生理检查结果的严重程度并不能预测随后的恢复速度。所有患者在第一个月内均有显著恢复（达到功能独立）。
