Liu Z, Hayano M, Hirata T, Quin Y, Tsukahara K, Ishimatsu T, Sakamoto R, Iliev I, Iwamoto K, Ueyama C, Yano K
Third Department of Internal Medicine, Nagasaki University School of Medicine.
J Cardiol. 1998 Sep;32(3):189-96.
In 39 patients with idiopathic paroxysmal atrial fibrillation (PAF group), the incidence of the abnormal P wave morphology (prolonged P wave and mitral P in lead II and increased P terminal force in lead V1: PTF V1) was examined, and the relationships to the electrophysiologic findings of the atrial muscle were investigated. The control group consisted of 42 patients with various cardiac arrhythmias other than sick sinus syndrome. P wave duration was significantly longer in the PAF group than in the control group (112 +/- 12 vs 98 +/- 10 msec, p < 0.0001). PTF V1 was greater in the PAF group than in the control group (0.051 +/- 0.018 vs 0.028 +/- 0.010 msec, p < 0.0001). P mitrale occurred in only 5 patients (12%) in the control group as compared to 25 patients in the PAF group (64%, p < 0.0001). The longest duration of the right atrial electrograms was longer in the PAF group than in the control group (101 +/- 17 vs 85 +/- 10 msec, p < 0.0001), as was the maximal number of the fragmented deflections (8.0 +/- 2.5 vs 5.8 +/- 1.4, p < 0.0001). Repetitive atrial firing zone and also fragmented atrial activity zone were longer in the PAF group than in the control group (34 +/- 24 vs 12 +/- 19 msec, p < 0.02 and 47 +/- 27 vs 24 +/- 19 msec, p < 0.001, respectively). Interatrial conduction delay zone was longer in the PAF group than in the control group (55 +/- 25 vs 38 +/- 18 msec, p < 0.001). P wave duration and PTF V1 had significant and/or borderline correlations with the longest duration of the right atrial electrocardiograms (r = 0.75, p < 0.0001 and r = 0.68, p < 0.0001, respectively), and the maximal number of its fragmented defections (r = 0.50, p < 0.002 and r = 0.40, p < 0.05, respectively). Furthermore, P wave duration had a correlation with the repetitive atrial firing zone (r = 0.55, p < 0.01). Prolonged P wave duration and increased PTF V1 are electrocardiographic indicators for the coexistence of electrophysiologic abnormalities in patients with idiopathic paroxysmal atrial fibrillation.
对39例特发性阵发性心房颤动患者(阵发性心房颤动组),检测异常P波形态(II导联P波延长和二尖瓣型P波、V1导联P波终末电势增大:PTF V1)的发生率,并研究其与心房肌电生理表现的关系。对照组由42例除病态窦房结综合征外的各种心律失常患者组成。阵发性心房颤动组的P波时限显著长于对照组(112±12 vs 98±10毫秒,p<0.0001)。阵发性心房颤动组的PTF V1大于对照组(0.051±0.018 vs 0.028±0.010毫秒,p<0.0001)。对照组仅5例患者(12%)出现二尖瓣型P波,而阵发性心房颤动组有25例患者(64%)出现,p<0.0001。阵发性心房颤动组右房电图的最长时限长于对照组(101±17 vs 85±10毫秒,p<0.0001),碎裂波的最大数量也更多(8.0±2.5 vs 5.8±1.4,p<0.0001)。阵发性心房颤动组的重复心房激动区和碎裂心房活动区也长于对照组(分别为34±24 vs 12±19毫秒,p<0.02和47±27 vs 24±19毫秒,p<0.001)。阵发性心房颤动组的房间传导延迟区长于对照组(55±25 vs 38±18毫秒,p<0.001)。P波时限和PTF V1与右房电图的最长时限(分别为r = 0.75,p<0.0001和r = 0.68,p<0.0001)及其碎裂波的最大数量(分别为r = 0.50,p<0.002和r = 0.40,p<0.05)有显著和/或临界相关性。此外,P波时限与重复心房激动区有关(r = 0.55,p<0.01)。P波时限延长和PTF V1增大是特发性阵发性心房颤动患者电生理异常共存的心电图指标。