带状疱疹和水痘-带状疱疹病毒感染后出现的大疱性多形红斑。

Bullous erythema multiforme following herpes zoster and varicella-zoster virus infection.

作者信息

Weisman K, Petersen C S, Blichmann C W, Nielsen N H, Hultberg B M

机构信息

Department of Dermato-Venereology, Bispebjerg Hospital, Copenhagen NV, Denmark.

出版信息

J Eur Acad Dermatol Venereol. 1998 Sep;11(2):147-50. doi: 10.1111/j.1468-3083.1998.tb00768.x.

DOI:10.1111/j.1468-3083.1998.tb00768.x

PMID:9784041

Abstract

Four cases of herpes zoster-induced bullous erythema multiforme (EM) are reported. Three patients presented with widespread skin lesions 10 to 14 days after an episode of thoracic herpes zoster. In these patients a high increase in varicella-zoster virus (VZV) antibody titer was detected, indicating secondary VZV infection. Histologic examinations of skin biopsy from a patient with widespread lesions (case 4) revealed a mixture of EM, toxic epidermal necrolysis and herpetic virus infection. VZV should be included in the list of infectious agents able to trigger EM and Stevens-Johnson syndrome.

摘要

报告了4例带状疱疹诱发的大疱性多形红斑（EM）。3例患者在胸部带状疱疹发作后10至14天出现广泛的皮肤病变。在这些患者中检测到水痘-带状疱疹病毒（VZV）抗体滴度大幅升高，表明继发VZV感染。对一名有广泛病变患者（病例4）的皮肤活检进行组织学检查，发现有EM、中毒性表皮坏死松解症和疱疹病毒感染的混合表现。VZV应列入能够引发EM和史蒂文斯-约翰逊综合征的感染因子名单中。