Kishore B Nanda, Ankadavar Nandini S, Kamath Ganesh H, Martis Jacintha
Department of Dermatology, Venereology & Leprosy, Father Muller Medical College, Kankanady, Mangalore, Karnataka, India.
Indian J Dermatol. 2014 May;59(3):299-301. doi: 10.4103/0019-5154.131415.
Erythema multiforme (EM) is an acute, self-limited, mucocutaneous disorder regarded as a hypersensitivity reaction which is triggered by various factors like infection, drugs, and food. Infectious agents are considered to be a major cause of EM other than idiopathic cause. A young girl presented with fluid-filled lesions all over the body of 3 days duration with history of similar lesions with fever in her sibling 2 weeks prior to admission. This was followed by large fluid-filled lesions with halo 3 days thereafter over the trunk, extremities suggesting target lesions of EM. The diagnosis was confirmed by cytology and positive serology. Varicella zoster virus (VZV) has rarely been reported as an etiological agent, despite its high incidence in childhood. VZV as an etiology of EM in a young girl has not been reported so far. This case was reported for its rare association of EM and varicella zoster and also for its rare presentation in a young girl.
多形红斑（EM）是一种急性、自限性的黏膜皮肤疾病，被视为由感染、药物和食物等多种因素引发的超敏反应。除特发性病因外，感染因子被认为是EM的主要病因。一名年轻女孩全身出现持续3天的充满液体的皮损，入院前2周其兄弟姐妹有类似皮损伴发热病史。此后3天，躯干和四肢出现带有晕圈的大的充满液体的皮损，提示为多形红斑的靶形皮损。通过细胞学检查和血清学阳性结果确诊。水痘带状疱疹病毒（VZV）尽管在儿童中发病率很高，但作为病因导致多形红斑的报道很少。迄今为止，尚未有VZV作为年轻女孩多形红斑病因的报道。报道此病例是因其多形红斑与水痘带状疱疹的罕见关联以及在年轻女孩中的罕见表现。
