可变性红斑角化病：病例报告及文献综述
Erythrokeratoderma variabilis: case report and review of the literature.
作者信息
Papadavid E, Koumantaki E, Dawber R P
机构信息
Dermatology Department, Churchill Hospital, Headington, Oxford, UK.
出版信息
J Eur Acad Dermatol Venereol. 1998 Sep;11(2):180-3.
We report two patients, mother and daughter, with Erythrokeratoderma variabilis (EV). This rare genodermatosis is characterized by the presence of two components: migratory erythema and fixed hyperkeratosis. Our patients experienced symptomatic relief of pruritus associated with erythema with the use of an oral, low-sedating H1-antihistamine. Revision of the literature in order to allocate the frequency of pruritus in EV and discussion of this association will follow.
我们报告了两名患有可变型红斑角化病（EV）的患者，分别是一对母女。这种罕见的遗传性皮肤病有两个特征：游走性红斑和固定性角化过度。我们的患者使用口服低镇静作用的H1抗组胺药后，与红斑相关的瘙痒症状得到缓解。接下来将查阅文献以确定EV中瘙痒的发生率，并对这种关联进行讨论。
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