拟精神病胺的硫类似物。

Sulfur analogs of psychotomimetic amines.

作者信息

Nichols D E, Shulgin A T

出版信息

J Pharm Sci. 1976 Oct;65(10):1554-6. doi: 10.1002/jps.2600651040.

Abstract

The syntheses and physical properties are described for 2,5-dimethoxy-4-methylthiophenylethylamine and 2,5-dimethoxy-4-methylthiophenylisopropylamine. The latter compound is the sulfur analog of the psychotomimetic phenylisopropylamines 2,4,5-trimethoxyphenylisopropylamine and 2,5-dimethoxy-4-methylphenylisopropylamine wherein the methylthio group replaces a methoxy group or a methyl group, respectively. This compound is predicted to be about 30 times as active as mescaline.

摘要

描述了2,5 - 二甲氧基 - 4 - 甲硫基苯乙胺和2,5 - 二甲氧基 - 4 - 甲硫基苯异丙胺的合成方法及物理性质。后一种化合物是致幻苯异丙胺类药物2,4,5 - 三甲氧基苯异丙胺和2,5 - 二甲氧基 - 4 - 甲基苯异丙胺的硫类似物，其中甲硫基分别取代了一个甲氧基或一个甲基。预计该化合物的活性约为三甲氧苯乙胺的30倍。