Gnudi G
Department of Electronics Informatics and Systems (DEIS), University of Bologna, Italy.
Comput Biol Med. 1998 May;28(3):207-23. doi: 10.1016/s0010-4825(98)00008-0.
New closed-form mathematical expressions, in the time- and frequency-domain, are derived for estimating the arterial windkessel compliance. The proposed expressions assume the three-element windkessel to model the arterial system and require the measurements of the entire waveforms of arterial pressure and flow. The resistance parameters are estimated using the recently proposed energy-balance method, then compliance is analytically calculated in order to minimize the pressure error in the compliant element. The derived expressions remain valid even when the windkessel compliance is assumed to be pressure-dependent. Also, it is shown that the method, either time- or frequency-domain formulation, provides parameter estimates, which minimize the arterial pressure square error. The method has been applied to simulated data as well as to pressure and flow data measured in the ascending aorta of three anaesthetized dogs under different circulatory conditions.
推导了用于估计动脉风箱顺应性的新的时域和频域闭式数学表达式。所提出的表达式假设用三元风箱对动脉系统进行建模，并需要测量动脉压力和流量的完整波形。使用最近提出的能量平衡方法估计阻力参数，然后通过解析计算顺应性，以最小化顺应元件中的压力误差。即使假设风箱顺应性与压力相关，所推导的表达式仍然有效。此外，结果表明，该方法无论是时域还是频域公式，都能提供使动脉压力平方误差最小化的参数估计。该方法已应用于模拟数据以及在不同循环条件下对三只麻醉犬升主动脉测量的压力和流量数据。
