Michel F, Toussirot E, Wendling D
Rheumatology Department, Jean Minjoz Teaching Hospital, Besançon, France.
Rev Rhum Engl Ed. 1998 Jul-Sep;65(7-9):504-7.
Systemic lupus erythematosus and primary biliary cirrhosis are two autoimmune disorders that rarely occur in the same patient. Ten well-documented cases have been reported to date. We add the case of a woman who was diagnosed with systemic lupus erythematosus at 54 years of age then with primary biliary cirrhosis 18 years later. Interestingly, primary biliary cirrhosis antedated the systemic lupus erythematosus in all the other reported cases. The possibility that a patient may develop more than one autoimmune disorder should be borne in mind.
系统性红斑狼疮和原发性胆汁性肝硬化是两种很少在同一患者身上出现的自身免疫性疾病。迄今为止,已有十例记录详实的病例报告。我们补充了一例病例,该女性54岁时被诊断为系统性红斑狼疮,18年后又患上原发性胆汁性肝硬化。有趣的是,在所有其他报告的病例中,原发性胆汁性肝硬化都早于系统性红斑狼疮。应牢记患者可能会患上不止一种自身免疫性疾病的可能性。