Schluter P J, Ford R P
N Z Med J. 1998 Sep 11;111(1073):336-40.
To determine whether New Zealand's goals for immunisation coverage are being met in Christchurch and to assess whether scheduled vaccinations are being delivered in a timely fashion.
A cohort of all infants born in Christchurch during June, July and August 1995 were matched with immunisation benefit claim information for the 6-week, 3-month, 5-month and 15-month immunisation events. Those with incomplete reports were traced for amendment or verification of their immunisation status.
The cohort contained 1002 infants. The full complement of scheduled immunisations was delivered to an estimated 95.8% (95% CI: 94.5, 97.2) of infants within the cohort by two years of age. Infants who presented late for their 6-week immunisation visits were significantly more likely to be late for their next visits (chi 2 log rank = 8.2, df = 1, p < 0.01), as were those late for their 3-month visits (chi 2 = 20.9, df = 1, p < 0.01), and their 5-month visits (chi 2 = 52.5, df = 1, p < 0.01). Infants were significantly less likely to receive their full complement of immunisations by two years of age if they presented late for their 6-week (Fisher's exact test, p = 0.01), 3-month (p < 0.01) or 5-month (p = 0.01) immunisation visits.
The Immunisation 2000 target of 95% full immunisation coverage by two years of age was met by this cohort. However, infants who were late for any immunisation visits were more likely to be late for subsequent visits and incompletely vaccinated by two years of age, compared to those infants who presented on time.
确定克赖斯特彻奇市是否实现了新西兰的免疫接种覆盖率目标,并评估计划内疫苗接种是否及时进行。
将1995年6月、7月和8月在克赖斯特彻奇市出生的所有婴儿组成一个队列,并与6周龄、3月龄、5月龄和15月龄免疫接种事件的免疫接种福利申领信息进行匹配。对报告不完整的婴儿进行追踪,以修正或核实其免疫接种状态。
该队列包含1002名婴儿。到两岁时,估计队列中95.8%(95%可信区间:94.5, 97.2)的婴儿完成了全部计划免疫接种。6周龄免疫接种就诊迟到的婴儿,下次就诊迟到的可能性显著更高(卡方对数秩检验=8.2,自由度=1,p<0.01),3月龄就诊迟到的婴儿也是如此(卡方=20.9,自由度=1,p<0.01),5月龄就诊迟到的婴儿同样如此(卡方=52.5,自由度=1,p<0.01)。如果婴儿6周龄(费舍尔精确检验,p=0.01)、3月龄(p<0.01)或5月龄(p=0.01)免疫接种就诊迟到,到两岁时他们完成全部免疫接种的可能性显著降低。
该队列实现了2000年免疫接种目标,即两岁时95%的完全免疫接种覆盖率。然而,与按时就诊的婴儿相比,任何一次免疫接种就诊迟到的婴儿后续就诊迟到的可能性更高,到两岁时疫苗接种也更不完整。